My wife, three boys, and I spent Memorial Day weekend in the Lake Wappapello region. We're from St. Louis but have actually never been to this area!
We were greatly impressed! Beth, the owner, takes extremely good care of the place! There are four bedrooms, two on the main level, two on the upper level, and two bathrooms.
The large kitchen is fully stocked with most common kitchen appliances and pretty much every utensil you can imagine. The living room is very roomy with a nice TV and there's also a firepit out back.
The area isn't really close to the lake or any conveniences except for a Dollar General down Highway D about half a mile. It's about a 15 minute drive to a "main area" with a gas station, a bar, a restaurant, and an ice cream shop. Chaonia Resort, which offers boat rentals, is about a 30 minute drive away.
Even though it's tucked away surrounded by mobile homes and gravel roads, the area is overall very quiet and very secluded.
We really enjoyed our stay! Beth is an awesome host and we will definitely consider staying at this lake house again when we come back to the area!